The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB00324 http://purl.obolibrary.org/obo/dinto_DB00324
Preferred Name	fluorometholone
Synonyms	C22H29FO4 (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	fluorometholone
label	fluorometholone
DBSynonym	fluormetholone fluoromethalone fml fluormetholon
ATCCode	C05AA06 D07XB04 S01BA07 S01CB05 D10AA01 D07AB06 See more See less
Definition	A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
has effect	http://purl.obolibrary.org/obo/OAE_0000589 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001481 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001073 http://purl.obolibrary.org/obo/OAE_0000312 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000466 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2874
induces	http://purl.obolibrary.org/obo/dinto_0901
activates	http://purl.obolibrary.org/obo/dinto_2874
type	http://www.w3.org/2002/07/owl#Class
InChIKey	InChIKey=FAOZLTXFLGPHNG-KNAQIMQKSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_0901
AHFScode	52:08.08
Synonym	C22H29FO4 (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
xref	Drugs Product Database (DPD):2238568 PubChem Substance:46505984 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/fml1183.shtml PubChem Compound:9878 Wikipedia:http://en.wikipedia.org/wiki/Fluorometholone National Drug Code Directory:11980-228-05 RxList:http://www.rxlist.com/cgi/generic/fluorometholone.htm Drugs.com:http://www.drugs.com/cdi/fluorometholone.html ChemSpider:9494 PharmGKB:PA164781355 See more See less
CASRN	426-13-1
prefixIRI	obo2:dinto_DB00324
related with	http://purl.obolibrary.org/obo/dinto_2146
SMILES	[H][C@@]12CC[C@](O)(C(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](C)C2=CC(=O)C=C[C@]12C
InChI	InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
DBBrand	loticort efflumidex trilcin cortilet fml forte fluor-op ursnon fml liquifilm flumetholon delmeson oxylone flarex fluaton See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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