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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00276
http://purl.obolibrary.org/obo/dinto_DB00276
|
|---|---|
| Preferred Name | amsacrine |
| Synonyms |
C21H19N3O3S
N-{4-[(acridin-9-yl)amino]-3-methoxyphenyl}methanesulfonamide
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | amsacrine
|
|---|---|
| label | amsacrine
|
| DBSynonym |
mamsa
m-amsa
acridinyl anisidide
|
| ATCCode | L01XX01
|
| Definition | Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects. [PubChem]
|
| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| InChIKey | InChIKey=XCPGHVQEEXUHNC-UHFFFAOYSA-N
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| is metabolised by | |
| AHFScode | 10:00.00
|
| Synonym |
C21H19N3O3S
N-{4-[(acridin-9-yl)amino]-3-methoxyphenyl}methanesulfonamide
|
| xref |
ChEBI:2687
ChemSpider:2094
PubChem Compound:2179
PharmGKB:PA10309
PubChem Substance:46507539
Drugs Product Database (DPD):582212
Wikipedia:http://en.wikipedia.org/wiki/Amsacrine
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| CASRN | 51264-14-3
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| prefixIRI | obo2:dinto_DB00276
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| related with | |
| SMILES | COC1=C(NC2=C3C=CC=CC3=NC3=CC=CC=C23)C=CC(NS(C)(=O)=O)=C1
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| may interact with | |
| InChI | InChI=1S/C21H19N3O3S/c1-27-20-13-14(24-28(2,25)26)11-12-19(20)23-21-15-7-3-5-9-17(15)22-18-10-6-4-8-16(18)21/h3-13,24H,1-2H3,(H,22,23)
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| DBBrand |
amsa p-d
amsine
amsidine
amsidyl
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |