The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB00220 http://purl.obolibrary.org/obo/dinto_DB00220
Preferred Name	nelfinavir
Synonyms	C32H45N3O4S (3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(phenylsulfanyl)butyl]-decahydroisoquinoline-3-carboxamide
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	nelfinavir
label	nelfinavir
DBSynonym	nelfinavir mesylate nlf nfv ag1343 1un
ATCCode	J05AE04
Definition	A potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. [PubChem]
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0001190 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000495 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0001403 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3326
induces	http://purl.obolibrary.org/obo/dinto_1440
inhibits	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_3326 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_2019 http://purl.obolibrary.org/obo/dinto_1987 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_0465 See more See less
type	http://www.w3.org/2002/07/owl#Class
InChIKey	InChIKey=QAGYKUNXZHXKMR-HKWSIXNMSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956
AHFScode	08:18.08.08
Synonym	C32H45N3O4S (3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(phenylsulfanyl)butyl]-decahydroisoquinoline-3-carboxamide
xref	RxList:http://www.rxlist.com/cgi/generic2/nelfin.htm National Drug Code Directory:63010-010-30 ChemSpider:57718 Drugs.com:http://www.drugs.com/cdi/nelfinavir.html BindingDB:518 PubChem Substance:46507719 Drugs Product Database (DPD):2248761 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/vir1483.shtml PubChem Compound:64143 Wikipedia:http://en.wikipedia.org/wiki/Nelfinavir PharmGKB:PA450606 See more See less
CASRN	159989-64-7
prefixIRI	obo2:dinto_DB00220
is transported by	http://purl.obolibrary.org/obo/dinto_1440
SMILES	[H][C@@]12CCCC[C@]1([H])CN(C[C@@H](O)[C@H](CSC1=CC=CC=C1)NC(=O)C1=C(C)C(O)=CC=C1)[C@@H](C2)C(=O)NC(C)(C)C
may interact with	http://purl.obolibrary.org/obo/dinto_DB00906 http://purl.obolibrary.org/obo/dinto_DB00683 http://purl.obolibrary.org/obo/CHEBI_8212 http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/CHEBI_391960 http://purl.obolibrary.org/obo/CHEBI_9948 http://purl.obolibrary.org/obo/CHEBI_9943 http://purl.obolibrary.org/obo/dinto_DB00801 http://purl.obolibrary.org/obo/CHEBI_585948 http://purl.obolibrary.org/obo/CHEBI_4317 http://purl.obolibrary.org/obo/CHEBI_71940 http://purl.obolibrary.org/obo/CHEBI_68642 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/dinto_DB00541 http://purl.obolibrary.org/obo/dinto_DB00243 http://purl.obolibrary.org/obo/CHEBI_499361 http://purl.obolibrary.org/obo/CHEBI_10127 http://purl.obolibrary.org/obo/dinto_DB01591 http://purl.obolibrary.org/obo/CHEBI_31547 http://purl.obolibrary.org/obo/CHEBI_4858 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/dinto_DB00726 http://purl.obolibrary.org/obo/CHEBI_9150 http://purl.obolibrary.org/obo/CHEBI_3756 http://purl.obolibrary.org/obo/dinto_DB06287 http://purl.obolibrary.org/obo/dinto_DB00342 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_63632 http://purl.obolibrary.org/obo/CHEBI_3611 http://purl.obolibrary.org/obo/CHEBI_68595 http://purl.obolibrary.org/obo/CHEBI_40303 http://purl.obolibrary.org/obo/dinto_DB01410 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/dinto_DB01323 http://purl.obolibrary.org/obo/dinto_DB00570 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/CHEBI_3761 http://purl.obolibrary.org/obo/CHEBI_10125 http://purl.obolibrary.org/obo/CHEBI_9654 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB01558 http://purl.obolibrary.org/obo/CHEBI_2611 http://purl.obolibrary.org/obo/CHEBI_75988 http://purl.obolibrary.org/obo/CHEBI_63637 http://purl.obolibrary.org/obo/dinto_DB08901 http://purl.obolibrary.org/obo/CHEBI_3720 http://purl.obolibrary.org/obo/dinto_DB01588 http://purl.obolibrary.org/obo/CHEBI_39548 http://purl.obolibrary.org/obo/CHEBI_480999 http://purl.obolibrary.org/obo/CHEBI_9622 http://purl.obolibrary.org/obo/CHEBI_6807 http://purl.obolibrary.org/obo/CHEBI_9398 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/CHEBI_32315 http://purl.obolibrary.org/obo/CHEBI_421707 http://purl.obolibrary.org/obo/CHEBI_28593 http://purl.obolibrary.org/obo/dinto_DB01118 http://purl.obolibrary.org/obo/CHEBI_9139 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/CHEBI_49575 http://purl.obolibrary.org/obo/dinto_DB00690 http://purl.obolibrary.org/obo/CHEBI_63584 http://purl.obolibrary.org/obo/CHEBI_2896 http://purl.obolibrary.org/obo/CHEBI_119915 http://purl.obolibrary.org/obo/CHEBI_50922 http://purl.obolibrary.org/obo/CHEBI_114785 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/dinto_DB02703 http://purl.obolibrary.org/obo/dinto_DB01589 http://purl.obolibrary.org/obo/dinto_DB01346 http://purl.obolibrary.org/obo/CHEBI_63613 http://purl.obolibrary.org/obo/CHEBI_9674 http://purl.obolibrary.org/obo/CHEBI_71272 http://purl.obolibrary.org/obo/CHEBI_38940 http://purl.obolibrary.org/obo/dinto_DB01341 http://purl.obolibrary.org/obo/CHEBI_64318 http://purl.obolibrary.org/obo/CHEBI_46295 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/CHEBI_4562 See more See less
InChI	InChI=1S/C32H45N3O4S/c1-21-25(15-10-16-28(21)36)30(38)33-26(20-40-24-13-6-5-7-14-24)29(37)19-35-18-23-12-9-8-11-22(23)17-27(35)31(39)34-32(2,3)4/h5-7,10,13-16,22-23,26-27,29,36-37H,8-9,11-12,17-20H2,1-4H3,(H,33,38)(H,34,39)/t22-,23+,26-,27-,29+/m0/s1
DBBrand	viracept
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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