The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

vidarabine
Synonyms

(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

C10H13N5O4

ID

http://purl.obolibrary.org/obo/dinto_DB00194

ATCCode

J05AB03

S01AD06

binds

http://purl.obolibrary.org/obo/dinto_2942

http://purl.obolibrary.org/obo/dinto_2873

http://purl.obolibrary.org/obo/dinto_2659

http://purl.obolibrary.org/obo/dinto_0378

http://purl.obolibrary.org/obo/dinto_3662

CASRN

24356-66-9

DBBrand

spongoadenosine

arasena-a

vira-a

vidarabin

DBSynonym

arabinoside adenine

arabinosyladenine

ara-atp

ara-a

9-beta-d-arabinofuranosyl-adenine

araadenosine

arabinosyl adenine

adenine arabinoside

Definition

A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus. [PubChem]

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2873

http://purl.obolibrary.org/obo/dinto_2659

http://purl.obolibrary.org/obo/dinto_0378

http://purl.obolibrary.org/obo/dinto_2942

InChI

InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1

InChIKey

InChIKey=OIRDTQYFTABQOQ-UHTZMRCNSA-N

induces

http://purl.obolibrary.org/obo/dinto_2659

http://purl.obolibrary.org/obo/dinto_0378

inhibits

http://purl.obolibrary.org/obo/dinto_2942

is metabolised by

http://purl.obolibrary.org/obo/dinto_3662

is substrate of

http://purl.obolibrary.org/obo/dinto_3662

label

vidarabine

prefixIRI

obo2:dinto_DB00194

prefLabel

vidarabine

related with

http://purl.obolibrary.org/obo/dinto_2873

SMILES

NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O

Synonym

(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

C10H13N5O4

xref

National Drug Code Directory:61570-367-71

PubChem Substance:46506630

Wikipedia:http://en.wikipedia.org/wiki/Vidarabine

RxList:http://www.rxlist.com/cgi/generic3/vidarabine.htm

Drugs.com:http://www.drugs.com/mtm/vidarabine-ophthalmic.html

PubChem Compound:32326

ChemSpider:29966

ChEBI:45327

PDB:RAB

PharmGKB:PA451876

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.065.950 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0015571 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014740 RH-MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039150 PDQ LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039150 PDQ LOOM
http://purl.bioontology.org/ontology/SNMI/C-55B50 SNMI LOOM
http://purl.bioontology.org/ontology/RXNORM/11194 RXNORM LOOM
http://www.co-ode.org/ontologies/galen#Vidarabine GALEN LOOM
http://purl.bioontology.org/ontology/NDDF/003014 NDDF LOOM
http://purl.obolibrary.org/obo/NCIT_C929 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D014740 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017798 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.583.138.900 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D014740 BERO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373759007 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB00194 MDM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C929 NCIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12991 OCHV LOOM
http://stirdf.jst.go.jp/id/200907073982852657 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/J05AB03 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4018650 VANDF LOOM
http://purl.jp/bio/4/id/200906014095932611 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0042646 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.759.590.138.900 RH-MESH LOOM
http://purl.obolibrary.org/obo/DRON_00012695 PDRO LOOM
http://purl.bioontology.org/ontology/ATC/S01AD06 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146963 NDFRT LOOM
http://purl.bioontology.org/ontology/RCD/x01Iz RCD LOOM