Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
Jump to:
| Id | http://purl.obolibrary.org/obo/dinto_DB00144
http://purl.obolibrary.org/obo/dinto_DB00144
|
|---|---|
| Preferred Name | phosphatidylserine |
| Synonyms |
(2S)-2-amino-3-({[(2R)-2-(butanoyloxy)-3-(propanoyloxy)propoxy](hydroxy)phosphoryl}oxy)propanoic acid
C13H24NO10P
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
phosphatidylserine
|
|---|---|
| prefLabel |
phosphatidylserine
|
| Definition |
Phosphatidylserine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase C (PKC) which has been shown to be involved in memory function. In apoptosis, phosphatidylserine is transferred to the outer leaflet of the plasma membrane. This is part of the process by which the cell is targeted for phagocytosis. PS has been shown to slow cognitive decline in animal models. PS has been investigated in a small number of double-blind placebo trials and has been shown to increase memory performance in the elderly. Because of the potentail cognitive benefits of phosphatidylserine, the substance is sold as a dietary supplement to people who believe they can benefit from an increased intake.
The dietary supplement was originally processed from bovine sources however Prion disease scares in the 1990s outlawed this process, and a soy-based alternative was adopted.
|
| DBBrand |
lifeextension ps caps
|
| SMILES |
CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
|
| InChI |
InChI=1S/C13H24NO10P/c1-3-5-12(16)24-9(6-21-11(15)4-2)7-22-25(19,20)23-8-10(14)13(17)18/h9-10H,3-8,14H2,1-2H3,(H,17,18)(H,19,20)/t9-,10+/m1/s1
|
| CASRN |
8002-43-5
|
| prefixIRI |
obo2:dinto_DB00144
|
| Synonym |
(2S)-2-amino-3-({[(2R)-2-(butanoyloxy)-3-(propanoyloxy)propoxy](hydroxy)phosphoryl}oxy)propanoic acid
C13H24NO10P
|
| binds |
See more
See less
|
| InChIKey |
InChIKey=UNJJBGNPUUVVFQ-ZJUUUORDSA-N
|
| subClassOf | |
| related with |
See more
See less
|
| type | |
| xref |
PubChem Compound:6323481
PDRhealth:http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/pho_0202.shtml
ChemSpider:13628254
Wikipedia:http://en.wikipedia.org/wiki/Phosphatidylserine
PharmGKB:PA164768860
Guide To Pharmacology:3638
PDB:PSF
PubChem Substance:46505650
IUPHAR:3638
ChEBI:18303
See more
See less
|
| DBSynonym |
o3-phosphatidyl-l-serine
phosphatidyl-l-serine
3-o-sn-phosphatidyl-l-serine
|
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |