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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00116
http://purl.obolibrary.org/obo/dinto_DB00116
|
|---|---|
| Preferred Name | tetrahydrofolic acid |
| Synonyms |
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
C19H23N7O6
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | tetrahydrofolic acid
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|---|---|
| label | tetrahydrofolic acid
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| DBSynonym |
5,6,7,8-tetrahydrofolate
5,6,7,8-tetrahydrofolic acid
tetrahydrofolate
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| Definition | Tetrahydrofolic acid is a folic acid derivative. It is produced from dihydrofolic acid by dihydrofolate reductase.
It is converted into 5,10-methylenetetrahydrofolate by serine hydroxymethyltransferase. It is a coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids. It acts as a donor of a group with one carbon atom. It gets this carbon atom by sequestering formaldehyde produced in other processes.
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| inhibits | |
| type | |
| InChIKey | InChIKey=MSTNYGQPCMXVAQ-KIYNQFGBSA-N
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| Synonym | (2S)-2-[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
C19H23N7O6
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| xref |
ChemSpider:82572
Wikipedia:http://en.wikipedia.org/wiki/Tetrahydrofolic_acid
PharmGKB:PA164745110
PubChem Compound:91443
PubChem Substance:46504756
ChEBI:20506
PDB:THL
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| CASRN | 135-16-0
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| prefixIRI | obo2:dinto_DB00116
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| related with |
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| SMILES | NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
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| InChI | InChI=1S/C19H23N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,11-12,21,23H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t11?,12-/m0/s1
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