Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00110
http://purl.obolibrary.org/obo/dinto_DB00110
|
|---|---|
| Preferred Name | palivizumab |
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | palivizumab
|
|---|---|
| label | palivizumab
|
| DBSynonym |
anti-rsv
synagis
|
| ATCCode | J06BB16
|
| Definition | Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains of human IgG1 and the variable framework regions of the VH genes Cor (1) and Cess (2). The human lightchain sequence was derived from the constant domain of Ck and the variable framework regions of the VL gene K104 withJk-4. Palivizumab is expressed from a stable murine (mouse) myeloma cell line (NS0). Palivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF)
|
| has pharmacological target | |
| type | |
| AHFScode | 08:18.24
|
| xref |
PharmGKB:PA164748781
Drugs.com:http://www.drugs.com/cdi/palivizumab.html
RxList:http://www.rxlist.com/cgi/generic2/palivizumab.htm
National Drug Code Directory:60574-4114-1
Drugs Product Database (DPD):2245889
Wikipedia:http://en.wikipedia.org/wiki/Palivizumab
See more
See less
|
| CASRN | 188039-54-5
|
| prefixIRI | obo2:dinto_DB00110
|
| related with |
See more
See less
|
| DBBrand | synagis
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |