The Drug-Drug Interactions Ontology - natalizumab - Classes | NCBO BioPortal

The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB00108 http://purl.obolibrary.org/obo/dinto_DB00108
Preferred Name	natalizumab
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	natalizumab
label	natalizumab
DBSynonym	anti-vla4 anti-alpha4 integrin
ATCCode	L04AA23
Definition	Humanized IgG4k monoclonal antibody produced in murine myeloma cells. Natalizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to a4-integrin. Natalizumab was voluntarily withdrawn from U.S. market because of risk of Progressive multifocal leukoencephalopathy (PML). It was returned to market July, 2006.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3988
type	http://www.w3.org/2002/07/owl#Class
AHFScode	92:00.00
xref	National Drug Code Directory:59075-730-15 Wikipedia:http://en.wikipedia.org/wiki/Natalizumab Drugs.com:http://www.drugs.com/cdi/natalizumab.html PharmGKB:PA164747191 Drugs Product Database (DPD):2286386 RxList:http://www.rxlist.com/cgi/generic/tysabri.htm See more See less
CASRN	189261-10-7
prefixIRI	obo2:dinto_DB00108
related with	http://purl.obolibrary.org/obo/dinto_3109 http://purl.obolibrary.org/obo/dinto_3105 http://purl.obolibrary.org/obo/dinto_3106 http://purl.obolibrary.org/obo/dinto_3107 http://purl.obolibrary.org/obo/dinto_3078 http://purl.obolibrary.org/obo/dinto_3084 http://purl.obolibrary.org/obo/dinto_3112 http://purl.obolibrary.org/obo/dinto_3111 http://purl.obolibrary.org/obo/dinto_3709 http://purl.obolibrary.org/obo/dinto_3988 http://purl.obolibrary.org/obo/dinto_0787 http://purl.obolibrary.org/obo/dinto_3466 See more See less
may interact with	http://purl.obolibrary.org/obo/dinto_DB00385 http://purl.obolibrary.org/obo/CHEBI_45863 http://purl.obolibrary.org/obo/dinto_DB00541 http://purl.obolibrary.org/obo/CHEBI_681569 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/dinto_DB00291 http://purl.obolibrary.org/obo/CHEBI_9513 http://purl.obolibrary.org/obo/dinto_DB06287 http://purl.obolibrary.org/obo/dinto_DB06674 http://purl.obolibrary.org/obo/CHEBI_63632 http://purl.obolibrary.org/obo/dinto_DB00081 http://purl.obolibrary.org/obo/dinto_DB00570 http://purl.obolibrary.org/obo/dinto_DB04572 http://purl.obolibrary.org/obo/dinto_DB00290 http://purl.obolibrary.org/obo/dinto_DB04865 http://purl.obolibrary.org/obo/dinto_DB08904 http://purl.obolibrary.org/obo/CHEBI_15367 http://purl.obolibrary.org/obo/CHEBI_567361 http://purl.obolibrary.org/obo/CHEBI_75988 http://purl.obolibrary.org/obo/dinto_DB05773 http://purl.obolibrary.org/obo/CHEBI_3423 http://purl.obolibrary.org/obo/CHEBI_480999 http://purl.obolibrary.org/obo/dinto_DB08870 http://purl.obolibrary.org/obo/dinto_DB06168 http://purl.obolibrary.org/obo/CHEBI_72564 http://purl.obolibrary.org/obo/CHEBI_68540 http://purl.obolibrary.org/obo/dinto_DB00072 http://purl.obolibrary.org/obo/CHEBI_27899 http://purl.obolibrary.org/obo/CHEBI_9555 http://purl.obolibrary.org/obo/CHEBI_31355 See more See less
DBBrand	tysabri
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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