The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_DB00074
http://purl.obolibrary.org/obo/dinto_DB00074
Preferred Name

basiliximab
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
basiliximab
label
basiliximab
DBSynonym
ig gamma-1 chain c region
chimeric mouse-human anticd25
ATCCode
L04AC02
Definition
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha.
has pharmacological target
type
AHFScode
92:00.00
xref
GenBank:J00228
Drugs.com:http://www.drugs.com/cdi/basiliximab.html
National Drug Code Directory:0078-0393-61
Drugs Product Database (DPD):2242815
Wikipedia:http://en.wikipedia.org/wiki/Basiliximab
UniProtKB:P01857
RxList:http://www.rxlist.com/cgi/generic2/basiliximab.htm
PharmGKB:PA164747126
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CASRN
152923-56-3
prefixIRI
obo2:dinto_DB00074
related with
may interact with
DBBrand
simulect (novartis pharmaceuticals)
subClassOf
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