The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	abciximab
Synonyms
ID	http://purl.obolibrary.org/obo/dinto_DB00054
AHFScode	92:00.00
ATCCode	B01AC13
binds	http://purl.obolibrary.org/obo/dinto_3109 http://purl.obolibrary.org/obo/dinto_3105 http://purl.obolibrary.org/obo/dinto_3106 http://purl.obolibrary.org/obo/dinto_3107 http://purl.obolibrary.org/obo/dinto_3078 http://purl.obolibrary.org/obo/dinto_0881 http://purl.obolibrary.org/obo/dinto_3084 http://purl.obolibrary.org/obo/dinto_3112 http://purl.obolibrary.org/obo/dinto_3111 http://purl.obolibrary.org/obo/dinto_3709 http://purl.obolibrary.org/obo/dinto_3461 http://purl.obolibrary.org/obo/dinto_3466 http://purl.obolibrary.org/obo/dinto_2013 http://purl.obolibrary.org/obo/dinto_1017
blocks	http://purl.obolibrary.org/obo/dinto_2013 http://purl.obolibrary.org/obo/dinto_1017
CASRN	143653-53-6
DBBrand	reopro
DBSynonym	c7e3 7e3 antibody 7e3 antigpiibiiia
Definition	Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (?v?3) receptor found on platelets and vessel wall endothelial and smooth muscle cells.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2013 http://purl.obolibrary.org/obo/dinto_1017
label	abciximab
may interact with	http://purl.obolibrary.org/obo/CHEBI_9605 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/dinto_DB00072 http://purl.obolibrary.org/obo/dinto_DB01381
modulates	http://purl.obolibrary.org/obo/dinto_2013 http://purl.obolibrary.org/obo/dinto_1017
prefixIRI	obo2:dinto_DB00054
prefLabel	abciximab
related with	http://purl.obolibrary.org/obo/dinto_3109 http://purl.obolibrary.org/obo/dinto_3105 http://purl.obolibrary.org/obo/dinto_3106 http://purl.obolibrary.org/obo/dinto_3107 http://purl.obolibrary.org/obo/dinto_3078 http://purl.obolibrary.org/obo/dinto_0881 http://purl.obolibrary.org/obo/dinto_3084 http://purl.obolibrary.org/obo/dinto_3112 http://purl.obolibrary.org/obo/dinto_3111 http://purl.obolibrary.org/obo/dinto_3709 http://purl.obolibrary.org/obo/dinto_3461 http://purl.obolibrary.org/obo/dinto_3466
xref	Drugs.com:http://www.drugs.com/cdi/abciximab.html National Drug Code Directory:0002-7140-01 RxList:http://www.rxlist.com/reopro-drug.htm Wikipedia:http://en.wikipedia.org/wiki/Abciximab PharmGKB:PA448006 Drugs Product Database (DPD):2216973
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/DRON_00012988	DRON	LOOM
http://purl.obolibrary.org/obo/DRON_00012988	PDRO	LOOM
http://purl.obolibrary.org/obo/DRON_00012988	DDSS	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#27755	OCHV	LOOM
http://purl.bioontology.org/ontology/ATC/B01AC13	ATC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148393	NDFRT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025409	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386951001	SNOMEDCT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C085843	RH-MESH	LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_8bc22209_b564_4f6f_b14b_4fbbb2731f82	STO-DRAFT	LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_8bc22209_b564_4f6f_b14b_4fbbb2731f82	CVAO	LOOM
https://go.drugbank.com/drugs/DB00054	MDM	LOOM
http://www.drugbank.ca/drugs/DB00054	FTC	LOOM
http://www.co-ode.org/ontologies/galen#Abciximab	GALEN	LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#abciximab	SDO	LOOM
http://purl.jp/bio/4/id/200906071817140972	IOBC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76128	NCIT	LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02642	MIO	LOOM
http://purl.obolibrary.org/obo/NCIT_C76128	BERO	LOOM
http://purl.bioontology.org/ontology/VANDF/4020901	VANDF	LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571352688529240170	ACVD_ONTOLOGY	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0288672	OCHV	LOOM
http://purl.bioontology.org/ontology/MESH/D000077284	MESH	LOOM
http://purl.bioontology.org/ontology/NDDF/004907	NDDF	LOOM
http://purl.bioontology.org/ontology/RXNORM/83929	RXNORM	LOOM
http://purl.bioontology.org/ontology/LNC/LP171382-7	LOINC	LOOM
http://purl.bioontology.org/ontology/RCD/bu3..	RCD	LOOM