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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00047
http://purl.obolibrary.org/obo/dinto_DB00047
|
|---|---|
| Preferred Name | insulin glargine |
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | insulin glargine
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|---|---|
| label | insulin glargine
|
| DBSynonym | insulin glargine (rdna origin)
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| ATCCode | A10AE04
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| Definition | Insulin glargine is produced by recombinant DNA technology using a non-pathogenic laboratory strain of Escherichia coli (K12) as the production organism. It is an analogue of human insulin made by replacing the asparagine residue at position A21 of the A-chain with glycine and adding two arginines to the C-terminus (positions B31 and 32) of the B-chain. The resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4. Small amounts of insulin glargine are slowly released from microprecipitates giving the drug a long duration of action (up to 24 hours) and no pronounced peak concentration.
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| has effect |
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| has pharmacological target | |
| induces | |
| activates | |
| type | |
| AHFScode | 68:20.08
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| xref |
Drugs Product Database (DPD):2245689
Drugs.com:http://www.drugs.com/cdi/insulin-glargine-cartridge-systems.html
Wikipedia:http://en.wikipedia.org/wiki/Insulin_glargine
National Drug Code Directory:0088-2220-60
RxList:http://www.rxlist.com/cgi/generic2/lantus.htm
PharmGKB:PA449992
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| CASRN | 160337-95-1
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| prefixIRI | obo2:dinto_DB00047
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| may interact with |
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| DBBrand |
lantus
lantus optiset
lantus solostar
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |