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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_DB00028
http://purl.obolibrary.org/obo/dinto_DB00028
|
|---|---|
| Preferred Name | intravenous immunoglobulin |
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | intravenous immunoglobulin
|
|---|---|
| label | intravenous immunoglobulin
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| DBSynonym |
immunoglobulin g
immune globulin
ig alpha-2 chain c region
|
| ATCCode |
J06BA02
J06BA01
|
| Definition | Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population. IgG subclasses are fully represented in the following proportions: 70.3% IgG1, 24.7% IgG2, 3.1% IgG3, and 1.9% IgG4. IVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders.
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| has pharmacological target |
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| type | |
| binds | |
| blocks |
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| AHFScode | 80:04.00
|
| xref |
Drugs Product Database (DPD):2230920
GenBank:J00221
PharmGKB:PA164754884
UniProtKB:P01877
National Drug Code Directory:67467-843-01
RxList:http://www.rxlist.com/cgi/generic2/baygam.htm
Drugs.com:http://www.drugs.com/cdi/immune-globulin-human.html
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| CASRN | 9007-83-4
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| prefixIRI | obo2:dinto_DB00028
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| DBBrand |
civacir
gamunex (talecris biotherapeutics)
flebogamma (instituto grifols sa)
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |