The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

anakinra
Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB00026
AHFScode

92:00.00
ATCCode

L04AC03
binds

http://purl.obolibrary.org/obo/dinto_3870
blocks

http://purl.obolibrary.org/obo/dinto_3870
CASRN

143090-92-0
DBBrand

kineret (amgen inc)
DBSynonym

icil-1ra

il1 inhibitor

il-1ra

irap

interleukin-1 receptor antagonist protein precursor

il-1rn
Definition

Anakinra is a recombinant, nonglycosylated human interleukin-1 receptor antagonist (IL-1Ra). The difference between anakinra and the native human IL-1Ra is that anakinra has an extra methionine residue at the amino terminus. It is manufactured by using the E. coli expression system. Anakinra is composed of 153 amino acid residues. FDA approved on November 14, 2001.
has pharmacological target

http://purl.obolibrary.org/obo/dinto_3870
label

anakinra
may interact with

http://purl.obolibrary.org/obo/CHEBI_9513

http://purl.obolibrary.org/obo/dinto_DB06674

http://purl.obolibrary.org/obo/dinto_DB08904

http://purl.obolibrary.org/obo/dinto_DB06372

http://purl.obolibrary.org/obo/dinto_DB06168

http://purl.obolibrary.org/obo/dinto_DB00072
modulates

http://purl.obolibrary.org/obo/dinto_3870
prefixIRI

obo2:dinto_DB00026
prefLabel

anakinra
xref

Drugs.com:http://www.drugs.com/cdi/anakinra.html

GenBank:M55646

Drugs Product Database (DPD):2245913

National Drug Code Directory:66658-234-28

PharmGKB:PA10799

RxList:http://www.rxlist.com/cgi/generic/anakinra.htm

Wikipedia:http://en.wikipedia.org/wiki/Anakinra

UniProtKB:P18510
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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