The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_DB00026 http://purl.obolibrary.org/obo/dinto_DB00026
Preferred Name	anakinra
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	anakinra
label	anakinra
DBSynonym	icil-1ra il1 inhibitor il-1ra irap interleukin-1 receptor antagonist protein precursor il-1rn See more See less
ATCCode	L04AC03
Definition	Anakinra is a recombinant, nonglycosylated human interleukin-1 receptor antagonist (IL-1Ra). The difference between anakinra and the native human IL-1Ra is that anakinra has an extra methionine residue at the amino terminus. It is manufactured by using the E. coli expression system. Anakinra is composed of 153 amino acid residues. FDA approved on November 14, 2001.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3870
type	http://www.w3.org/2002/07/owl#Class
blocks	http://purl.obolibrary.org/obo/dinto_3870
AHFScode	92:00.00
xref	Drugs.com:http://www.drugs.com/cdi/anakinra.html GenBank:M55646 Drugs Product Database (DPD):2245913 National Drug Code Directory:66658-234-28 PharmGKB:PA10799 RxList:http://www.rxlist.com/cgi/generic/anakinra.htm Wikipedia:http://en.wikipedia.org/wiki/Anakinra UniProtKB:P18510 See more See less
CASRN	143090-92-0
prefixIRI	obo2:dinto_DB00026
may interact with	http://purl.obolibrary.org/obo/CHEBI_9513 http://purl.obolibrary.org/obo/dinto_DB06674 http://purl.obolibrary.org/obo/dinto_DB08904 http://purl.obolibrary.org/obo/dinto_DB06372 http://purl.obolibrary.org/obo/dinto_DB06168 http://purl.obolibrary.org/obo/dinto_DB00072 See more See less
DBBrand	kineret (amgen inc)
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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