The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

lepirudin
Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB00001

AHFScode

20:12.04.12

ATCCode

B01AE02

binds

http://purl.obolibrary.org/obo/dinto_1008

CASRN

120993-53-5

DBBrand

refludan

DBSynonym

hirudin variant-1

Definition

Lepirudin is identical to natural hirudin except for substitution of leucine for isoleucine at the N-terminal end of the molecule and the absence of a sulfate group on the tyrosine at position 63. It is produced via yeast cells.

has effect

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0001189

http://purl.obolibrary.org/obo/OAE_0000905

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000318

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000650

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0001360

http://purl.obolibrary.org/obo/OAE_0001707

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0001013

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0001064

http://purl.obolibrary.org/obo/OAE_0000197

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0001538

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000690

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0001396

http://purl.obolibrary.org/obo/OAE_0001340

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0001003

http://purl.obolibrary.org/obo/OAE_0001014

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001281

http://purl.obolibrary.org/obo/OAE_0000469

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000968

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0001434

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0000185

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000618

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0001364

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1008

inhibits

http://purl.obolibrary.org/obo/dinto_1008

label

lepirudin

may interact with

http://purl.obolibrary.org/obo/CHEBI_50861

http://purl.obolibrary.org/obo/dinto_DB01381

prefixIRI

obo2:dinto_DB00001

prefLabel

lepirudin

xref

Drugs.com:http://www.drugs.com/cdi/lepirudin.html

Wikipedia:http://en.wikipedia.org/wiki/Lepirudin

RxList:http://www.rxlist.com/cgi/generic/lepirudin.htm

National Drug Code Directory:50419-150-57

UniProtKB:P01050

Drugs Product Database (DPD):2240996

PharmGKB:PA450195

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_142437 DRON LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043356 PDQ LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#48816 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C083544 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_142437 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_142437 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_142437 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_142437 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_142437 DDSS LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025401 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RXNORM/237057 RXNORM LOOM
http://purl.bioontology.org/ontology/NDDF/007520 NDDF LOOM
http://purl.bioontology.org/ontology/LNC/LP171615-0 LOINC LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02637 MIO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02637 MIO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02637 MIO LOOM
http://purl.bioontology.org/ontology/ATC/B01AE02 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0772394 OCHV LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Lepirudin SEPON LOOM
http://purl.bioontology.org/ontology/VANDF/4021096 VANDF LOOM
https://go.drugbank.com/drugs/DB00001 MDM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148552 NDFRT LOOM
http://purl.obolibrary.org/obo/NCIT_C1839 BERO LOOM
http://www.co-ode.org/ontologies/galen#Lepirudin GALEN LOOM
http://www.drugbank.ca/drugs/DB00001 FTC LOOM
http://purl.jp/bio/4/id/201306034051700490 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/C083544 MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1839 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386955005 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RCD/brA.. RCD LOOM