The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	siroheme synthase
Synonyms
ID	http://purl.obolibrary.org/obo/dinto_4187
binds	http://purl.obolibrary.org/obo/dinto_DB01907 http://purl.obolibrary.org/obo/dinto_DB01752 http://purl.obolibrary.org/obo/dinto_DB04522
Definition	Multifunctional enzyme that catalyze the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consist of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme
definition source	DrugBank Database
Gene	cysg
label	siroheme synthase
OrganismClass	bacterial
prefixIRI	obo2:dinto_4187
prefLabel	siroheme synthase
related with	http://purl.obolibrary.org/obo/dinto_DB01907 http://purl.obolibrary.org/obo/dinto_DB01752 http://purl.obolibrary.org/obo/dinto_DB04522
xref	UniProt ID:P25924 DrugBank:4318
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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Delete	Mapping To	Ontology	Source
	http://purl.obolibrary.org/obo/PR_000025879	PR	LOOM
	http://purl.obolibrary.org/obo/PR_000025879	NIFSTD	LOOM