Preferred Name | hemagglutinin | |
Synonyms |
hemagglutinin ha1 chain fragment hemagglutinin ha2 chain |
|
ID |
http://purl.obolibrary.org/obo/dinto_4166 |
|
binds | ||
Definition |
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore |
|
definition source |
DrugBank Database |
|
Gene | ||
label |
hemagglutinin |
|
OrganismClass |
viral |
|
prefixIRI |
obo2:dinto_4166 |
|
prefLabel |
hemagglutinin |
|
related with | ||
Synonym |
hemagglutinin ha1 chain fragment hemagglutinin ha2 chain |
|
xref |
UniProt ID:P26137 DrugBank:6566 |
|
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://sbmi.uth.tmc.edu/ontology/ochv#C0018909 | OCHV | LOOM | |
http://sbmi.uth.tmc.edu/ontology/ochv#5934 | OCHV | LOOM | |
http://purl.bioontology.org/ontology/CSP/1556-1606 | CRISP | LOOM | |
http://purl.obolibrary.org/obo/FLU_0001028 | FLU | LOOM | |
http://purl.jp/bio/4/id/200906030627561124 | IOBC | LOOM |