The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_4111 http://purl.obolibrary.org/obo/dinto_4111
Preferred Name	tetanus toxin
Synonyms	tentoxylysin ec 3.4.24.68 tetanus toxin precursor
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	tetanus toxin
label	tetanus toxin
Definition	Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-\|-Phe- 77' bond of synaptobrevin-2
type	http://www.w3.org/2002/07/owl#Class
Synonym	tentoxylysin ec 3.4.24.68 tetanus toxin precursor
OrganismClass	bacterial
xref	UniProt ID:P04958 DrugBank:2570
definition source	DrugBank Database
prefixIRI	obo2:dinto_4111
related with	http://purl.obolibrary.org/obo/dinto_DB01894 http://purl.obolibrary.org/obo/dinto_DB04465 http://purl.obolibrary.org/obo/dinto_DB03721 http://purl.obolibrary.org/obo/dinto_DB02265 http://purl.obolibrary.org/obo/dinto_DB04265 http://purl.obolibrary.org/obo/dinto_DB02379 See more See less
Gene	tetx
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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