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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_4077
http://purl.obolibrary.org/obo/dinto_4077
|
|---|---|
| Preferred Name | granzyme b |
| Synonyms |
c11
ec 3.4.21.79
sect
human lymphocyte protein
hlp
lymphocyte protease
ctsgl1
granzyme b precursor
cathepsin g-like 1
t-cell serine protease 1-3e
granzyme-2
ctla-1
fragmentin-2
cytotoxic t-lymphocyte proteinase 2
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | granzyme b
|
|---|---|
| label | granzyme b
|
| Definition | This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis
|
| type | |
| Synonym |
c11
ec 3.4.21.79
sect
human lymphocyte protein
hlp
lymphocyte protease
ctsgl1
granzyme b precursor
cathepsin g-like 1
t-cell serine protease 1-3e
granzyme-2
ctla-1
fragmentin-2
cytotoxic t-lymphocyte proteinase 2
See more
See less
|
| OrganismClass | human
|
| xref |
UniProt ID:P10144
DrugBank:1072
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_4077
|
| related with | |
| Gene | gzmb
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |