The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/dinto_4052
http://purl.obolibrary.org/obo/dinto_4052
Preferred Name

aldo-keto reductase family 1 member c3
Synonyms
3-alpha- hydroxysteroid dehydrogenase type 2
3-alpha-hsd type ii, brain
dihydrodiol dehydrogenase type i
17-beta-hsd 5
chlordecone reductase homolog hakrb
3-alpha-hsd type 2
ha1753
ec 1.3.1.20
pgfs
estradiol 17-beta-dehydrogenase
ec 1.1.1.188
dd3
prostaglandin f synthase
17-beta-hydroxysteroid dehydrogenase type 5
ec 1.-.-.-
dihydrodiol dehydrogenase 3
ec 1.1.1.62
trans-1,2- dihydrobenzene-1,2-diol dehydrogenase
ec 1.1.1.213
dd-3
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Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
aldo-keto reductase family 1 member c3
label
aldo-keto reductase family 1 member c3
is induced by
metabolizes
Definition
Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9alpha,11beta- PGF2 to PGD2. Functions as a bi-directional 3alpha-, 17beta- and 20alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone
type
Synonym
3-alpha- hydroxysteroid dehydrogenase type 2
3-alpha-hsd type ii, brain
dihydrodiol dehydrogenase type i
17-beta-hsd 5
chlordecone reductase homolog hakrb
3-alpha-hsd type 2
ha1753
ec 1.3.1.20
pgfs
estradiol 17-beta-dehydrogenase
ec 1.1.1.188
dd3
prostaglandin f synthase
17-beta-hydroxysteroid dehydrogenase type 5
ec 1.-.-.-
dihydrodiol dehydrogenase 3
ec 1.1.1.62
trans-1,2- dihydrobenzene-1,2-diol dehydrogenase
ec 1.1.1.213
dd-3
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See less
OrganismClass
human
xref
UniProt ID:P42330
DrugBank:650
definition source
DrugBank Database
prefixIRI
obo2:dinto_4052
related with
Gene
akr1c3
subClassOf
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