The Drug-Drug Interactions Ontology - kappa-type opioid receptor - Classes | NCBO BioPortal

The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	kappa-type opioid receptor
Synonyms	kor-1
ID	http://purl.obolibrary.org/obo/dinto_3960
Definition	Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions
definition source	DrugBank Database
Gene	oprk1
is activated by	http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/dinto_DB00652 http://purl.obolibrary.org/obo/CHEBI_8802 http://purl.obolibrary.org/obo/CHEBI_4912 http://purl.obolibrary.org/obo/CHEBI_53763 http://purl.obolibrary.org/obo/CHEBI_17303 http://purl.obolibrary.org/obo/CHEBI_3242 http://purl.obolibrary.org/obo/CHEBI_7852 http://purl.obolibrary.org/obo/CHEBI_61084 http://purl.obolibrary.org/obo/dinto_DB00854 http://purl.obolibrary.org/obo/dinto_DB01565 http://purl.obolibrary.org/obo/CHEBI_5790 http://purl.obolibrary.org/obo/CHEBI_6532 http://purl.obolibrary.org/obo/CHEBI_7454 http://purl.obolibrary.org/obo/CHEBI_9648 http://purl.obolibrary.org/obo/CHEBI_27808 http://purl.obolibrary.org/obo/CHEBI_6950 http://purl.obolibrary.org/obo/CHEBI_61092 http://purl.obolibrary.org/obo/CHEBI_15409 http://purl.obolibrary.org/obo/CHEBI_119915 http://purl.obolibrary.org/obo/CHEBI_32091 http://purl.obolibrary.org/obo/CHEBI_2666
is blocked by	http://purl.obolibrary.org/obo/CHEBI_3216 http://purl.obolibrary.org/obo/dinto_DB06800 http://purl.obolibrary.org/obo/CHEBI_8497 http://purl.obolibrary.org/obo/CHEBI_7465 http://purl.obolibrary.org/obo/CHEBI_4474 http://purl.obolibrary.org/obo/CHEBI_7459 http://purl.obolibrary.org/obo/dinto_DB01548 http://purl.obolibrary.org/obo/dinto_DB06274
is pharmacological target of	http://purl.obolibrary.org/obo/CHEBI_3216 http://purl.obolibrary.org/obo/dinto_DB00652 http://purl.obolibrary.org/obo/CHEBI_16714 http://purl.obolibrary.org/obo/CHEBI_8497 http://purl.obolibrary.org/obo/CHEBI_4912 http://purl.obolibrary.org/obo/CHEBI_53763 http://purl.obolibrary.org/obo/CHEBI_17303 http://purl.obolibrary.org/obo/CHEBI_7465 http://purl.obolibrary.org/obo/CHEBI_3242 http://purl.obolibrary.org/obo/CHEBI_7852 http://purl.obolibrary.org/obo/dinto_DB00454 http://purl.obolibrary.org/obo/CHEBI_4474 http://purl.obolibrary.org/obo/CHEBI_5790 http://purl.obolibrary.org/obo/CHEBI_6532 http://purl.obolibrary.org/obo/CHEBI_7454 http://purl.obolibrary.org/obo/CHEBI_7459 http://purl.obolibrary.org/obo/CHEBI_61092
label	kappa-type opioid receptor
OrganismClass	human
prefixIRI	obo2:dinto_3960
prefLabel	kappa-type opioid receptor
related with	http://purl.obolibrary.org/obo/CHEBI_16714 http://purl.obolibrary.org/obo/CHEBI_9316 http://purl.obolibrary.org/obo/dinto_DB06204 http://purl.obolibrary.org/obo/dinto_DB00454
Synonym	kor-1
xref	UniProt ID:P41145 DrugBank:696
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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Delete	Mapping To	Ontology	Source
	http://purl.obolibrary.org/obo/PR_000001590	GO-PLUS	LOOM
	http://purl.obolibrary.org/obo/PR_000001590	GO-PLUS	LOOM
	http://www.drugtargetontology.org/dto/DTO_02100469	DTO	LOOM
	http://purl.obolibrary.org/obo/PR_000001590	PR	LOOM
	http://purl.obolibrary.org/obo/PR_000001590	INBANCIDO	LOOM
	http://purl.obolibrary.org/obo/PR_000001590	CIDO	LOOM
	http://purl.obolibrary.org/obo/PR_000001590	NIFSTD	LOOM
	http://www.bioassayontology.org/bao#BAO_0200128	BAO-GPCR	LOOM
	http://purl.uniprot.org/uniprot/P41145	FTC	LOOM