The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_3943 http://purl.obolibrary.org/obo/dinto_3943
Preferred Name	poly [adp-ribose] polymerase 1
Synonyms	parp-1 poly[adp-ribose] synthetase 1 ec 2.4.2.30 adprt nad(+) adp-ribosyltransferase 1
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	poly [adp-ribose] polymerase 1
label	poly [adp-ribose] polymerase 1
Definition	Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks
type	http://www.w3.org/2002/07/owl#Class
Synonym	parp-1 poly[adp-ribose] synthetase 1 ec 2.4.2.30 adprt nad(+) adp-ribosyltransferase 1
is binded by	http://purl.obolibrary.org/obo/CHEBI_17154
OrganismClass	human
xref	DrugBank:3126 UniProt ID:P09874
definition source	DrugBank Database
prefixIRI	obo2:dinto_3943
related with	http://purl.obolibrary.org/obo/dinto_DB07330 http://purl.obolibrary.org/obo/dinto_DB03072 http://purl.obolibrary.org/obo/dinto_DB07232 http://purl.obolibrary.org/obo/dinto_DB03722 http://purl.obolibrary.org/obo/dinto_DB07096 http://purl.obolibrary.org/obo/dinto_DB07787 http://purl.obolibrary.org/obo/dinto_DB03509 http://purl.obolibrary.org/obo/dinto_DB02498 http://purl.obolibrary.org/obo/dinto_DB03073 http://purl.obolibrary.org/obo/dinto_DB02690 http://purl.obolibrary.org/obo/dinto_DB04010 See more See less
Gene	parp1
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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