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loading...| Preferred Name | interleukin-1 receptor type i | |
| Synonyms |
il-1r-1 il-1rt1 cd121a antigen il-1r- alpha p80 interleukin-1 receptor type i precursor |
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| ID |
http://purl.obolibrary.org/obo/dinto_3870 |
|
| Definition |
Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2 |
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| definition source |
DrugBank Database |
|
| Gene |
il1r1 |
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| is binded by | ||
| is blocked by | ||
| is modulated by | ||
| is pharmacological target of | ||
| label |
interleukin-1 receptor type i |
|
| OrganismClass |
human |
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| prefixIRI |
obo2:dinto_3870 |
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| prefLabel |
interleukin-1 receptor type i |
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| Synonym |
il-1r-1 il-1rt1 cd121a antigen il-1r- alpha p80 interleukin-1 receptor type i precursor |
|
| xref |
DrugBank:622 UniProt ID:P14778 |
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| subClassOf |
Create mapping
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/PR_000001363 | NIFSTD | LOOM | |
| http://purl.uniprot.org/uniprot/P14778 | FTC | LOOM | |
| http://purl.bioontology.org/ontology/OMIM/147810 | OMIM | LOOM |