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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3869
http://purl.obolibrary.org/obo/dinto_3869
|
|---|---|
| Preferred Name | spermine oxidase |
| Synonyms |
polyamine oxidase 1
paoh1
ec 1.5.3.-
pao-1
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | spermine oxidase
|
|---|---|
| label | spermine oxidase
|
| Definition | Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use 1-N-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal
|
| type | |
| Synonym |
polyamine oxidase 1
paoh1
ec 1.5.3.-
pao-1
|
| OrganismClass | human
|
| xref |
DrugBank:623
UniProt ID:Q9NWM0
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3869
|
| related with | |
| is pharmacological target of | |
| Gene | smox
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |