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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3798
http://purl.obolibrary.org/obo/dinto_3798
|
|---|---|
| Preferred Name | rna 3'-terminal phosphate cyclase |
| Synonyms |
ec 6.5.1.4
rna-3'-phosphate cyclase
rna cyclase
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | rna 3'-terminal phosphate cyclase
|
|---|---|
| label | rna 3'-terminal phosphate cyclase
|
| Definition | Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps:(A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing
|
| type | |
| Synonym |
ec 6.5.1.4
rna-3'-phosphate cyclase
rna cyclase
|
| OrganismClass | bacterial
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| xref |
UniProt ID:P46849
DrugBank:5583
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3798
|
| related with | |
| Gene | rtca
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| subClassOf |
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| No notes to display |