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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3643
http://purl.obolibrary.org/obo/dinto_3643
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|---|---|
| Preferred Name | g protein-activated inward rectifier potassium channel 4 |
| Synonyms |
cardiac inward rectifier
girk4
inward rectifier k(+
cir
heart katp channel
katp-1
potassium channel, inwardly rectifying subfamily j member 5
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | g protein-activated inward rectifier potassium channel 4
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|---|---|
| label | g protein-activated inward rectifier potassium channel 4
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| Definition | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium
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| type | |
| is inhibited by | |
| Synonym |
cardiac inward rectifier
girk4
inward rectifier k(+
cir
heart katp channel
katp-1
potassium channel, inwardly rectifying subfamily j member 5
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| OrganismClass | human
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| xref |
UniProt ID:P48544
DrugBank:3961
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_3643
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| Gene | kcnj5
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| subClassOf |
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