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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3617
http://purl.obolibrary.org/obo/dinto_3617
|
|---|---|
| Preferred Name | peptidyl-glycine alpha-amidating monooxygenase |
| Synonyms |
pam
peptidylamidoglycolate lyase
peptidyl-glycine alpha-amidating monooxygenase precursor
peptidyl-alpha-hydroxyglycine alpha-amidating lyase (ec 4.3.2.5
ec 1.14.17.3
phm)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | peptidyl-glycine alpha-amidating monooxygenase
|
|---|---|
| label | peptidyl-glycine alpha-amidating monooxygenase
|
| Definition | Bifunctional enzyme that catalyzes 2 sequencial steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity
|
| type | |
| Synonym |
pam
peptidylamidoglycolate lyase
peptidyl-glycine alpha-amidating monooxygenase precursor
peptidyl-alpha-hydroxyglycine alpha-amidating lyase (ec 4.3.2.5
ec 1.14.17.3
phm)
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|
| OrganismClass | human
|
| xref |
UniProt ID:P19021
DrugBank:3943
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3617
|
| related with | |
| Gene | pam
|
| subClassOf |
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