The Drug-Drug Interactions Ontology - amine oxidase [flavin-containing] a - Classes | NCBO BioPortal

The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_3613 http://purl.obolibrary.org/obo/dinto_3613
Preferred Name	amine oxidase [flavin-containing] a
Synonyms	ec 1.4.3.4 monoamine oxidase type a mao-a
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	amine oxidase [flavin-containing] a
label	amine oxidase [flavin-containing] a
is induced by	http://purl.obolibrary.org/obo/dinto_DB00624
metabolizes	http://purl.obolibrary.org/obo/CHEBI_8093 http://purl.obolibrary.org/obo/CHEBI_520985 http://purl.obolibrary.org/obo/CHEBI_48273 http://purl.obolibrary.org/obo/CHEBI_10650 http://purl.obolibrary.org/obo/CHEBI_7478 http://purl.obolibrary.org/obo/CHEBI_18243 http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_9123 http://purl.obolibrary.org/obo/CHEBI_10124 See more See less
Definition	Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine
type	http://www.w3.org/2002/07/owl#Class
is inhibited by	http://purl.obolibrary.org/obo/dinto_DB01472 http://purl.obolibrary.org/obo/dinto_DB01442 http://purl.obolibrary.org/obo/dinto_DB04832 http://purl.obolibrary.org/obo/CHEBI_10127 http://purl.obolibrary.org/obo/CHEBI_18723 http://purl.obolibrary.org/obo/dinto_DB01626 http://purl.obolibrary.org/obo/CHEBI_8080 http://purl.obolibrary.org/obo/CHEBI_51038 http://purl.obolibrary.org/obo/CHEBI_51209 http://purl.obolibrary.org/obo/CHEBI_5195 http://purl.obolibrary.org/obo/dinto_DB01363 http://purl.obolibrary.org/obo/dinto_DB00397 http://purl.obolibrary.org/obo/dinto_DB01247 http://purl.obolibrary.org/obo/dinto_DB01577 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/CHEBI_63607 http://purl.obolibrary.org/obo/dinto_DB01171 http://purl.obolibrary.org/obo/dinto_DB01037 http://purl.obolibrary.org/obo/dinto_DB08804 See more See less
Synonym	ec 1.4.3.4 monoamine oxidase type a mao-a
OrganismClass	human
xref	UniProt ID:P21397 DrugBank:3941
definition source	DrugBank Database
prefixIRI	obo2:dinto_3613
related with	http://purl.obolibrary.org/obo/CHEBI_3210 http://purl.obolibrary.org/obo/CHEBI_116225 http://purl.obolibrary.org/obo/CHEBI_17015 http://purl.obolibrary.org/obo/dinto_DB03147 http://purl.obolibrary.org/obo/CHEBI_3763 http://purl.obolibrary.org/obo/dinto_DB04820 http://purl.obolibrary.org/obo/dinto_DB07919 http://purl.obolibrary.org/obo/dinto_DB07641 See more See less
is pharmacological target of	http://purl.obolibrary.org/obo/dinto_DB01442 http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_8080 http://purl.obolibrary.org/obo/CHEBI_51038 http://purl.obolibrary.org/obo/dinto_DB01363 http://purl.obolibrary.org/obo/dinto_DB01247 http://purl.obolibrary.org/obo/dinto_DB01577 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/dinto_DB01171 See more See less
is blocked by	http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_8080
Gene	maoa
subClassOf	http://purl.obolibrary.org/obo/dinto_000130 http://purl.obolibrary.org/obo/dinto_000128

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