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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3513
http://purl.obolibrary.org/obo/dinto_3513
|
|---|---|
| Preferred Name | fk506-binding protein 1a |
| Synonyms |
fkbp-12
peptidyl-prolyl cis-trans isomerase
rotamase
immunophilin fkbp12
ppiase
ec 5.2.1.8
12 kda fkbp
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | fk506-binding protein 1a
|
|---|---|
| label | fk506-binding protein 1a
|
| Definition | May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
|
| type | |
| is inhibited by | |
| Synonym |
fkbp-12
peptidyl-prolyl cis-trans isomerase
rotamase
immunophilin fkbp12
ppiase
ec 5.2.1.8
12 kda fkbp
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|
| OrganismClass | human
|
| xref |
UniProt ID:P62942
DrugBank:768
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3513
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| related with |
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| is pharmacological target of | |
| Gene | fkbp1a
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |