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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3496
http://purl.obolibrary.org/obo/dinto_3496
|
|---|---|
| Preferred Name | cysteinyl leukotriene receptor 1 |
| Synonyms |
hg55
ltd4 receptor
hmtmf81
cysteinyl leukotriene d4 receptor
cysltr1
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | cysteinyl leukotriene receptor 1
|
|---|---|
| label | cysteinyl leukotriene receptor 1
|
| Definition | Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4
|
| type | |
| Synonym |
hg55
ltd4 receptor
hmtmf81
cysteinyl leukotriene d4 receptor
cysltr1
|
| OrganismClass | human
|
| xref |
DrugBank:778
UniProt ID:Q9Y271
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3496
|
| related with | |
| is pharmacological target of | |
| is blocked by | |
| Gene | cysltr1
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| subClassOf |
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| No notes to display |