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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3464
http://purl.obolibrary.org/obo/dinto_3464
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|---|---|
| Preferred Name | atp-sensitive inward rectifier potassium channel 11 |
| Synonyms |
ikatp
potassium channel, inwardly rectifying subfamily j member 11
inward rectifier k(+) channel kir6.2
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | atp-sensitive inward rectifier potassium channel 11
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|---|---|
| label | atp-sensitive inward rectifier potassium channel 11
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| is induced by | |
| Definition | This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium
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| type | |
| is modulated by | |
| is inhibited by | |
| Synonym |
ikatp
potassium channel, inwardly rectifying subfamily j member 11
inward rectifier k(+) channel kir6.2
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| OrganismClass | human
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| xref |
UniProt ID:Q14654
DrugBank:781
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_3464
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| is pharmacological target of | |
| Gene | kcnj11
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| subClassOf |
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