The Drug-Drug Interactions Ontology - interferon-alpha/beta receptor alpha chain - Classes | NCBO BioPortal

The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	interferon-alpha/beta receptor alpha chain
Synonyms	ifn-alpha-rec interferon-alpha/beta receptor alpha chain precursor
ID	http://purl.obolibrary.org/obo/dinto_3330
binds	http://purl.obolibrary.org/obo/dinto_DB00034
Definition	Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta- subunits themselves
definition source	DrugBank Database
Gene	ifnar1
is activated by	http://purl.obolibrary.org/obo/dinto_DB00011 http://purl.obolibrary.org/obo/dinto_DB00018 http://purl.obolibrary.org/obo/dinto_DB00022 http://purl.obolibrary.org/obo/dinto_DB00008 http://purl.obolibrary.org/obo/dinto_DB00068 http://purl.obolibrary.org/obo/dinto_DB00060
is binded by	http://purl.obolibrary.org/obo/dinto_DB00069 http://purl.obolibrary.org/obo/dinto_DB00105 http://purl.obolibrary.org/obo/dinto_DB00011 http://purl.obolibrary.org/obo/dinto_DB00034 http://purl.obolibrary.org/obo/dinto_DB00018 http://purl.obolibrary.org/obo/dinto_DB00022 http://purl.obolibrary.org/obo/dinto_DB00008 http://purl.obolibrary.org/obo/dinto_DB00068 http://purl.obolibrary.org/obo/dinto_DB00060
is modulated by	http://purl.obolibrary.org/obo/dinto_DB00011 http://purl.obolibrary.org/obo/dinto_DB00018 http://purl.obolibrary.org/obo/dinto_DB00022 http://purl.obolibrary.org/obo/dinto_DB00008 http://purl.obolibrary.org/obo/dinto_DB00068 http://purl.obolibrary.org/obo/dinto_DB00060
is pharmacological target of	http://purl.obolibrary.org/obo/dinto_DB00069 http://purl.obolibrary.org/obo/dinto_DB00011 http://purl.obolibrary.org/obo/dinto_DB00034 http://purl.obolibrary.org/obo/dinto_DB00105 http://purl.obolibrary.org/obo/dinto_DB00018 http://purl.obolibrary.org/obo/dinto_DB00022 http://purl.obolibrary.org/obo/dinto_DB00008 http://purl.obolibrary.org/obo/dinto_DB00068 http://purl.obolibrary.org/obo/dinto_DB00060
label	interferon-alpha/beta receptor alpha chain
OrganismClass	human
prefixIRI	obo2:dinto_3330
prefLabel	interferon-alpha/beta receptor alpha chain
related with	http://purl.obolibrary.org/obo/dinto_DB00034
Synonym	ifn-alpha-rec interferon-alpha/beta receptor alpha chain precursor
xref	UniProt ID:P17181 DrugBank:728
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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Delete	Mapping To	Ontology	Source
	http://purl.uniprot.org/uniprot/P17181	FTC	LOOM
	http://purl.obolibrary.org/obo/PR_000008922	PR	LOOM
	http://purl.obolibrary.org/obo/PR_000008922	INBANCIDO	LOOM
	http://purl.obolibrary.org/obo/PR_000008922	HOIP	LOOM
	http://purl.obolibrary.org/obo/PR_000008922	CIDO	LOOM
	http://purl.obolibrary.org/obo/PR_000008922	NIFSTD	LOOM