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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3162
http://purl.obolibrary.org/obo/dinto_3162
|
|---|---|
| Preferred Name | nuclear receptor subfamily 1 group i member 2 |
| Synonyms |
pregnane x receptor
orphan nuclear receptor par1
sxr
steroid and xenobiotic receptor
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | nuclear receptor subfamily 1 group i member 2
|
|---|---|
| label | nuclear receptor subfamily 1 group i member 2
|
| is induced by | |
| Definition | Orphan receptor; its natural ligand is probably pregnane. Binds to a response element in the CYP3A4 and ABCB1/MDR1 genes promoter. Activates its expression in response to a wide variety of endobiotics and xenobiotics
|
| type | |
| is activated by | |
| Synonym |
pregnane x receptor
orphan nuclear receptor par1
sxr
steroid and xenobiotic receptor
|
| OrganismClass | human
|
| xref |
UniProt ID:O75469
DrugBank:1284
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3162
|
| related with | |
| is pharmacological target of | |
| Gene | nr1i2
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |