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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3161
http://purl.obolibrary.org/obo/dinto_3161
|
|---|---|
| Preferred Name | phosphatidylinositol 3-kinase regulatory subunit alpha |
| Synonyms |
pi3k
pi3-kinase p85-subunit alpha
ptdins-3-kinase p85-alpha
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | phosphatidylinositol 3-kinase regulatory subunit alpha
|
|---|---|
| label | phosphatidylinositol 3-kinase regulatory subunit alpha
|
| Definition | Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues
|
| type | |
| is activated by | |
| Synonym |
pi3k
pi3-kinase p85-subunit alpha
ptdins-3-kinase p85-alpha
|
| OrganismClass | human
|
| xref |
DrugBank:1281
UniProt ID:P27986
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3161
|
| related with | |
| Gene | pik3r1
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |