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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3143
http://purl.obolibrary.org/obo/dinto_3143
|
|---|---|
| Preferred Name | prostaglandin e2 receptor, ep3 subtype |
| Synonyms |
pge2-r
prostanoid ep3 receptor
pge receptor, ep3 subtype
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | prostaglandin e2 receptor, ep3 subtype
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|---|---|
| label | prostaglandin e2 receptor, ep3 subtype
|
| Definition | Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity)
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| type | |
| is activated by | |
| Synonym |
pge2-r
prostanoid ep3 receptor
pge receptor, ep3 subtype
|
| OrganismClass | human
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| xref |
UniProt ID:P43115
DrugBank:4131
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_3143
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| is pharmacological target of | |
| Gene | ptger3
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| subClassOf |
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| No notes to display |