Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3118
http://purl.obolibrary.org/obo/dinto_3118
|
|---|---|
| Preferred Name | potassium voltage-gated channel subfamily kqt member 5 |
| Synonyms |
voltage-gated potassium channel subunit kv7.5
kqt-like 5
potassium channel subunit alpha kvlqt5
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | potassium voltage-gated channel subfamily kqt member 5
|
|---|---|
| label | potassium voltage-gated channel subfamily kqt member 5
|
| Definition | Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. May contribute, with other potassium channels, to the molecular diversity of an heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. Muscarine suppresses KCNQ5 current in Xenopus oocytes in which cloned KCNQ5 channels were coexpressed with M(1) muscarinic receptors
|
| type | |
| Synonym |
voltage-gated potassium channel subunit kv7.5
kqt-like 5
potassium channel subunit alpha kvlqt5
|
| OrganismClass | human
|
| xref |
UniProt ID:Q9NR82
DrugBank:4164
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3118
|
| related with | |
| Gene | kcnq5
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |