The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_3100 http://purl.obolibrary.org/obo/dinto_3100
Preferred Name	catechol o-methyltransferase
Synonyms	ec 2.1.1.6
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	catechol o-methyltransferase
label	catechol o-methyltransferase
metabolizes	http://purl.obolibrary.org/obo/CHEBI_600520 http://purl.obolibrary.org/obo/CHEBI_4670 http://purl.obolibrary.org/obo/CHEBI_18243 http://purl.obolibrary.org/obo/CHEBI_41922 http://purl.obolibrary.org/obo/dinto_DB00286 http://purl.obolibrary.org/obo/CHEBI_61058 See more See less
Definition	Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol
type	http://www.w3.org/2002/07/owl#Class
is inhibited by	http://purl.obolibrary.org/obo/CHEBI_63630 http://purl.obolibrary.org/obo/CHEBI_4798 http://purl.obolibrary.org/obo/dinto_DB01420
Synonym	ec 2.1.1.6
OrganismClass	human
xref	UniProt ID:P21964 DrugBank:3810
definition source	DrugBank Database
prefixIRI	obo2:dinto_3100
related with	http://purl.obolibrary.org/obo/dinto_DB07462 http://purl.obolibrary.org/obo/dinto_DB03336 http://purl.obolibrary.org/obo/dinto_DB02105 http://purl.obolibrary.org/obo/dinto_DB03907 http://purl.obolibrary.org/obo/dinto_DB08049 http://purl.obolibrary.org/obo/dinto_DB04820 http://purl.obolibrary.org/obo/CHEBI_15414 See more See less
is pharmacological target of	http://purl.obolibrary.org/obo/CHEBI_63630 http://purl.obolibrary.org/obo/CHEBI_4798
Gene	comt
subClassOf	http://purl.obolibrary.org/obo/dinto_000130 http://purl.obolibrary.org/obo/dinto_000128

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