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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3078
http://purl.obolibrary.org/obo/dinto_3078
|
|---|---|
| Preferred Name | low affinity immunoglobulin gamma fc region receptor ii-b |
| Synonyms |
fcrii-b
fc-gamma rii-b
igg fc receptor ii-b
low affinity immunoglobulin gamma fc region receptor ii-b precursor
cd32 antigen
cdw32
fc-gamma-riib
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | low affinity immunoglobulin gamma fc region receptor ii-b
|
|---|---|
| label | low affinity immunoglobulin gamma fc region receptor ii-b
|
| Definition | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis
|
| type | |
| Synonym |
fcrii-b
fc-gamma rii-b
igg fc receptor ii-b
low affinity immunoglobulin gamma fc region receptor ii-b precursor
cd32 antigen
cdw32
fc-gamma-riib
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|
| OrganismClass | human
|
| xref |
UniProt ID:P31994
DrugBank:3820
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3078
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| related with |
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| is pharmacological target of | |
| is blocked by | |
| Gene | fcgr2b
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| subClassOf |
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| No notes to display |