The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

calreticulin
Synonyms

grp60

calreticulin precursor

crp55

erp60

hacbp

calregulin

ID

http://purl.obolibrary.org/obo/dinto_3059

binds

http://purl.obolibrary.org/obo/CHEBI_16796

http://purl.obolibrary.org/obo/dinto_DB00031

http://purl.obolibrary.org/obo/dinto_DB00025

Definition

Molecular calcium binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export

definition source

DrugBank Database

Gene

calr

label

calreticulin

OrganismClass

human

prefixIRI

obo2:dinto_3059

prefLabel

calreticulin

related with

http://purl.obolibrary.org/obo/CHEBI_16796

http://purl.obolibrary.org/obo/dinto_DB00031

http://purl.obolibrary.org/obo/dinto_DB00025

Synonym

grp60

calreticulin precursor

crp55

erp60

hacbp

calregulin

xref

DrugBank:3830

UniProt ID:P27797

subClassOf

http://purl.obolibrary.org/obo/dinto_000128

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