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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_3005
http://purl.obolibrary.org/obo/dinto_3005
|
|---|---|
| Preferred Name | histone deacetylase 6 |
| Synonyms |
hd6
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | histone deacetylase 6
|
|---|---|
| label | histone deacetylase 6
|
| Definition | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin
|
| type | |
| is inhibited by | |
| Synonym | hd6
|
| OrganismClass | human
|
| xref |
UniProt ID:Q9UBN7
DrugBank:4124
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_3005
|
| is pharmacological target of | |
| Gene | hdac6
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |