Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2966
http://purl.obolibrary.org/obo/dinto_2966
|
|---|---|
| Preferred Name | chaperone clpb |
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | chaperone clpb
|
|---|---|
| label | chaperone clpb
|
| Definition | Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Acts before dnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of clpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by dnaK
|
| type | |
| OrganismClass | bacterial
|
| xref |
UniProt ID:Q9RA63
DrugBank:5642
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_2966
|
| related with | |
| Gene | clpb
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |