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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2913
http://purl.obolibrary.org/obo/dinto_2913
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|---|---|
| Preferred Name | sodium channel protein type 10 subunit alpha |
| Synonyms |
peripheral nerve sodium channel 3
hpn3
sodium channel protein type x subunit alpha
voltage-gated sodium channel subunit alpha nav1.8
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | sodium channel protein type 10 subunit alpha
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|---|---|
| label | sodium channel protein type 10 subunit alpha
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| Definition | This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Its electrophysiological properties vary depending on the type of the associated beta subunits (in vitro). Plays a role in neuropathic pain mechanisms
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| Synonym |
peripheral nerve sodium channel 3
hpn3
sodium channel protein type x subunit alpha
voltage-gated sodium channel subunit alpha nav1.8
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| OrganismClass | human
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| xref |
DrugBank:198
UniProt ID:Q9Y5Y9
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_2913
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| related with | |
| is pharmacological target of |
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| Gene | scn10a
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| subClassOf |
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