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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2874
http://purl.obolibrary.org/obo/dinto_2874
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|---|---|
| Preferred Name | glucocorticoid receptor |
| Synonyms |
gr
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | glucocorticoid receptor
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|---|---|
| label | glucocorticoid receptor
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| Definition | Receptor for glucocorticoids (GC). Has a dual mode of action:as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth
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| type | |
| is activated by |
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| Synonym | gr
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| OrganismClass | human
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| xref |
UniProt ID:P04150
DrugBank:871
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| definition source | DrugBank Database
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| prefixIRI | obo2:dinto_2874
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| related with | |
| is pharmacological target of |
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| is blocked by | |
| Gene | nr3c1
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| subClassOf |
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| No notes to display |