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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2864
http://purl.obolibrary.org/obo/dinto_2864
|
|---|---|
| Preferred Name | sphingosine 1-phosphate receptor edg-8 |
| Synonyms |
sphingosine 1-phosphate receptor 5
s1p5
endothelial differentiation sphingolipid g-protein-coupled receptor 8
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | sphingosine 1-phosphate receptor edg-8
|
|---|---|
| label | sphingosine 1-phosphate receptor edg-8
|
| Definition | Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells
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| type | |
| is modulated by | |
| Synonym |
sphingosine 1-phosphate receptor 5
s1p5
endothelial differentiation sphingolipid g-protein-coupled receptor 8
|
| OrganismClass | human
|
| xref |
DrugBank:4199
UniProt ID:Q9H228
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| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_2864
|
| is pharmacological target of | |
| Gene | s1pr5
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |