The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	estrogen receptor
Synonyms	er-alpha er estradiol receptor
ID	http://purl.obolibrary.org/obo/dinto_2827
binds	http://purl.obolibrary.org/obo/dinto_DB07708 http://purl.obolibrary.org/obo/dinto_DB07712 http://purl.obolibrary.org/obo/dinto_DB08398 http://purl.obolibrary.org/obo/CHEBI_28088 http://purl.obolibrary.org/obo/dinto_DB08048 http://purl.obolibrary.org/obo/dinto_DB04471 http://purl.obolibrary.org/obo/dinto_DB06927 http://purl.obolibrary.org/obo/dinto_DB07087 http://purl.obolibrary.org/obo/dinto_DB07991 http://purl.obolibrary.org/obo/dinto_DB06898 http://purl.obolibrary.org/obo/dinto_DB03802 http://purl.obolibrary.org/obo/dinto_DB08320 http://purl.obolibrary.org/obo/dinto_DB07707 http://purl.obolibrary.org/obo/dinto_DB07195 http://purl.obolibrary.org/obo/dinto_DB02615 http://purl.obolibrary.org/obo/dinto_DB07933 http://purl.obolibrary.org/obo/dinto_DB07638 http://purl.obolibrary.org/obo/dinto_DB08773 http://purl.obolibrary.org/obo/dinto_DB08047 http://purl.obolibrary.org/obo/dinto_DB07932 http://purl.obolibrary.org/obo/dinto_DB07567 http://purl.obolibrary.org/obo/dinto_DB07086 http://purl.obolibrary.org/obo/dinto_DB07678 http://purl.obolibrary.org/obo/CHEBI_7459 http://purl.obolibrary.org/obo/dinto_DB08020 http://purl.obolibrary.org/obo/CHEBI_32260 http://purl.obolibrary.org/obo/CHEBI_6443 http://purl.obolibrary.org/obo/dinto_DB02715 http://purl.obolibrary.org/obo/dinto_DB06871 http://purl.obolibrary.org/obo/dinto_DB08595 http://purl.obolibrary.org/obo/dinto_DB08737 http://purl.obolibrary.org/obo/dinto_DB03742
Definition	Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues
definition source	DrugBank Database
Gene	esr1
is activated by	http://purl.obolibrary.org/obo/CHEBI_4315 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_6715 http://purl.obolibrary.org/obo/CHEBI_3641 http://purl.obolibrary.org/obo/dinto_DB04573 http://purl.obolibrary.org/obo/dinto_DB01431 http://purl.obolibrary.org/obo/dinto_DB04574 http://purl.obolibrary.org/obo/CHEBI_3752 http://purl.obolibrary.org/obo/CHEBI_8772 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/dinto_DB00890 http://purl.obolibrary.org/obo/CHEBI_31580 http://purl.obolibrary.org/obo/CHEBI_50815 http://purl.obolibrary.org/obo/CHEBI_41922 http://purl.obolibrary.org/obo/dinto_DB00783 http://purl.obolibrary.org/obo/CHEBI_17263 http://purl.obolibrary.org/obo/CHEBI_73275 http://purl.obolibrary.org/obo/dinto_DB04575 http://purl.obolibrary.org/obo/dinto_DB00286 http://purl.obolibrary.org/obo/CHEBI_50777 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/CHEBI_17026 http://purl.obolibrary.org/obo/CHEBI_4868 http://purl.obolibrary.org/obo/CHEBI_4453
is binded by	http://purl.obolibrary.org/obo/CHEBI_4315 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_6715 http://purl.obolibrary.org/obo/CHEBI_3641 http://purl.obolibrary.org/obo/dinto_DB04573 http://purl.obolibrary.org/obo/dinto_DB04574 http://purl.obolibrary.org/obo/CHEBI_3752 http://purl.obolibrary.org/obo/CHEBI_8772 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/dinto_DB00890 http://purl.obolibrary.org/obo/CHEBI_5120 http://purl.obolibrary.org/obo/CHEBI_31580 http://purl.obolibrary.org/obo/CHEBI_50815 http://purl.obolibrary.org/obo/CHEBI_9635 http://purl.obolibrary.org/obo/CHEBI_41922 http://purl.obolibrary.org/obo/dinto_DB00783 http://purl.obolibrary.org/obo/CHEBI_17263 http://purl.obolibrary.org/obo/CHEBI_73275 http://purl.obolibrary.org/obo/dinto_DB04575 http://purl.obolibrary.org/obo/dinto_DB00286 http://purl.obolibrary.org/obo/CHEBI_50777 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/CHEBI_17026 http://purl.obolibrary.org/obo/CHEBI_32260 http://purl.obolibrary.org/obo/CHEBI_6443 http://purl.obolibrary.org/obo/CHEBI_4868 http://purl.obolibrary.org/obo/CHEBI_4453 http://purl.obolibrary.org/obo/CHEBI_31638 http://purl.obolibrary.org/obo/CHEBI_16796 http://purl.obolibrary.org/obo/CHEBI_7459 http://purl.obolibrary.org/obo/dinto_DB01431
is blocked by	http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_3752 http://purl.obolibrary.org/obo/CHEBI_16796 http://purl.obolibrary.org/obo/CHEBI_5120 http://purl.obolibrary.org/obo/CHEBI_7459 http://purl.obolibrary.org/obo/CHEBI_73275 http://purl.obolibrary.org/obo/CHEBI_31638
is modulated by	http://purl.obolibrary.org/obo/CHEBI_9635 http://purl.obolibrary.org/obo/dinto_DB04575 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_3752 http://purl.obolibrary.org/obo/CHEBI_16796 http://purl.obolibrary.org/obo/CHEBI_5120 http://purl.obolibrary.org/obo/CHEBI_7459 http://purl.obolibrary.org/obo/CHEBI_73275 http://purl.obolibrary.org/obo/CHEBI_31638 http://purl.obolibrary.org/obo/CHEBI_4315 http://purl.obolibrary.org/obo/CHEBI_6715 http://purl.obolibrary.org/obo/CHEBI_3641 http://purl.obolibrary.org/obo/dinto_DB04573 http://purl.obolibrary.org/obo/dinto_DB01431 http://purl.obolibrary.org/obo/dinto_DB04574 http://purl.obolibrary.org/obo/CHEBI_8772 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/dinto_DB00890 http://purl.obolibrary.org/obo/CHEBI_31580 http://purl.obolibrary.org/obo/CHEBI_50815 http://purl.obolibrary.org/obo/CHEBI_41922 http://purl.obolibrary.org/obo/dinto_DB00783 http://purl.obolibrary.org/obo/CHEBI_17263 http://purl.obolibrary.org/obo/dinto_DB00286 http://purl.obolibrary.org/obo/CHEBI_50777 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/CHEBI_17026 http://purl.obolibrary.org/obo/CHEBI_4868 http://purl.obolibrary.org/obo/CHEBI_4453
is pharmacological target of	http://purl.obolibrary.org/obo/CHEBI_4315 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_6715 http://purl.obolibrary.org/obo/CHEBI_3641 http://purl.obolibrary.org/obo/dinto_DB04573 http://purl.obolibrary.org/obo/dinto_DB04574 http://purl.obolibrary.org/obo/CHEBI_3752 http://purl.obolibrary.org/obo/CHEBI_8772 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/dinto_DB00890 http://purl.obolibrary.org/obo/CHEBI_5120 http://purl.obolibrary.org/obo/CHEBI_31580 http://purl.obolibrary.org/obo/CHEBI_50815 http://purl.obolibrary.org/obo/CHEBI_9635 http://purl.obolibrary.org/obo/CHEBI_41922 http://purl.obolibrary.org/obo/dinto_DB00783 http://purl.obolibrary.org/obo/CHEBI_17263 http://purl.obolibrary.org/obo/CHEBI_73275 http://purl.obolibrary.org/obo/dinto_DB04575 http://purl.obolibrary.org/obo/dinto_DB00286 http://purl.obolibrary.org/obo/CHEBI_50777 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/CHEBI_17026 http://purl.obolibrary.org/obo/CHEBI_32260 http://purl.obolibrary.org/obo/CHEBI_6443 http://purl.obolibrary.org/obo/CHEBI_4868 http://purl.obolibrary.org/obo/CHEBI_4453 http://purl.obolibrary.org/obo/CHEBI_31638
label	estrogen receptor
OrganismClass	human
prefixIRI	obo2:dinto_2827
prefLabel	estrogen receptor
related with	http://purl.obolibrary.org/obo/dinto_DB07708 http://purl.obolibrary.org/obo/dinto_DB07712 http://purl.obolibrary.org/obo/dinto_DB08398 http://purl.obolibrary.org/obo/CHEBI_28088 http://purl.obolibrary.org/obo/dinto_DB08048 http://purl.obolibrary.org/obo/dinto_DB04471 http://purl.obolibrary.org/obo/dinto_DB06927 http://purl.obolibrary.org/obo/dinto_DB07087 http://purl.obolibrary.org/obo/dinto_DB07991 http://purl.obolibrary.org/obo/dinto_DB06898 http://purl.obolibrary.org/obo/dinto_DB03802 http://purl.obolibrary.org/obo/dinto_DB08320 http://purl.obolibrary.org/obo/dinto_DB07707 http://purl.obolibrary.org/obo/dinto_DB07195 http://purl.obolibrary.org/obo/dinto_DB02615 http://purl.obolibrary.org/obo/dinto_DB07933 http://purl.obolibrary.org/obo/dinto_DB07638 http://purl.obolibrary.org/obo/dinto_DB08773 http://purl.obolibrary.org/obo/dinto_DB08047 http://purl.obolibrary.org/obo/dinto_DB07932 http://purl.obolibrary.org/obo/dinto_DB07567 http://purl.obolibrary.org/obo/dinto_DB07086 http://purl.obolibrary.org/obo/dinto_DB07678 http://purl.obolibrary.org/obo/CHEBI_7459 http://purl.obolibrary.org/obo/dinto_DB08020 http://purl.obolibrary.org/obo/CHEBI_32260 http://purl.obolibrary.org/obo/CHEBI_6443 http://purl.obolibrary.org/obo/dinto_DB02715 http://purl.obolibrary.org/obo/dinto_DB06871 http://purl.obolibrary.org/obo/dinto_DB08595 http://purl.obolibrary.org/obo/dinto_DB08737 http://purl.obolibrary.org/obo/dinto_DB03742
Synonym	er-alpha er estradiol receptor
xref	UniProt ID:P03372 DrugBank:136
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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Mapping To	Ontology	Source
http://purl.jp/bio/4/id/200906026230374860	IOBC	LOOM
http://www.semanticweb.org/david/ontologies/2013/0/pathLex.owl#1.3.6.1.4.1.19376.1.8.2.1.432	PATHLEX	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000322903	PDQ	LOOM
http://dicom.nema.org/resources/ontology/DCM/111475	DCM	LOOM
http://purl.bioontology.org/ontology/CSP/2573-2460	CRISP	LOOM
http://www.drugtargetontology.org/dto/DTO_00117511	DTO	LOOM
http://purl.obolibrary.org/obo/MCBCC_0000031#Estrogen_receptor	MCBCC	LOOM
http://purl.obolibrary.org/obo/IMR_0000088	HOIP	LOOM
http://purl.obolibrary.org/obo/IMR_0000088	TXPO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0034804	OCHV	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004667	LOINC	LOOM
http://purl.uniprot.org/uniprot/P03372	FTC	LOOM
http://www.projecthalo.com/aura#Estrogen-Receptor	AURA	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/23307004	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/LNC/LP18567-5	LOINC	LOOM
http://purl.obolibrary.org/obo/PR_000007204	CL	LOOM
http://purl.obolibrary.org/obo/PR_000007204	PR	LOOM
http://purl.obolibrary.org/obo/PR_000007204	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/PR_000007204	BMONT	LOOM
http://purl.obolibrary.org/obo/PR_000007204	HHEAR	LOOM
http://purl.obolibrary.org/obo/PR_000007204	CIDO	LOOM
http://purl.obolibrary.org/obo/PR_000007204	NIFSTD	LOOM
http://purl.obolibrary.org/obo/PR_000007204	GO-PLUS	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38361	NCIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C38361	BERO	LOOM