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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2808
http://purl.obolibrary.org/obo/dinto_2808
|
|---|---|
| Preferred Name | histamine h2 receptor |
| Synonyms |
h2r
gastric receptor i
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | histamine h2 receptor
|
|---|---|
| label | histamine h2 receptor
|
| Definition | The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway
|
| type | |
| is activated by | |
| Synonym |
h2r
gastric receptor i
|
| OrganismClass | human
|
| xref |
UniProt ID:P25021
DrugBank:124
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_2808
|
| is pharmacological target of |
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| is blocked by |
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|
| Gene | hrh2
|
| subClassOf |
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| No notes to display |