The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_2574 http://purl.obolibrary.org/obo/dinto_2574
Preferred Name	angiotensin-converting enzyme 2
Synonyms	ec 3.4.17.- angiotensin-converting enzyme 2 precursor angiotensin-converting enzyme homolog ace-related carboxypeptidase aceh
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	angiotensin-converting enzyme 2
label	angiotensin-converting enzyme 2
Definition	Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses
type	http://www.w3.org/2002/07/owl#Class
is inhibited by	http://purl.obolibrary.org/obo/dinto_DB00691 http://purl.obolibrary.org/obo/CHEBI_43755
Synonym	ec 3.4.17.- angiotensin-converting enzyme 2 precursor angiotensin-converting enzyme homolog ace-related carboxypeptidase aceh
OrganismClass	human
xref	DrugBank:1385 UniProt ID:Q9BYF1
definition source	DrugBank Database
prefixIRI	obo2:dinto_2574
is pharmacological target of	http://purl.obolibrary.org/obo/dinto_DB00691 http://purl.obolibrary.org/obo/CHEBI_43755
Gene	ace2
subClassOf	http://purl.obolibrary.org/obo/dinto_000128

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