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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Preferred Name | transforming growth factor beta-1 | |
| Synonyms |
transforming growth factor beta-1 precursor tgf-beta-1 |
|
| ID |
http://purl.obolibrary.org/obo/dinto_2570 |
|
| Definition |
Multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts
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|
| definition source |
DrugBank Database
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|
| Gene |
tgfb1
|
|
| is binded by | ||
| is inhibited by | ||
| label |
transforming growth factor beta-1
|
|
| OrganismClass |
human
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|
| prefixIRI |
obo2:dinto_2570
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|
| prefLabel |
transforming growth factor beta-1
|
|
| Synonym |
transforming growth factor beta-1 precursor tgf-beta-1
|
|
| xref |
UniProt ID:P01137 DrugBank:1389
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|
| subClassOf |
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