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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/dinto_2570
http://purl.obolibrary.org/obo/dinto_2570
|
|---|---|
| Preferred Name | transforming growth factor beta-1 |
| Synonyms |
transforming growth factor beta-1 precursor
tgf-beta-1
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | transforming growth factor beta-1
|
|---|---|
| label | transforming growth factor beta-1
|
| Definition | Multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts
|
| type | |
| is inhibited by | |
| Synonym |
transforming growth factor beta-1 precursor
tgf-beta-1
|
| OrganismClass | human
|
| xref |
UniProt ID:P01137
DrugBank:1389
|
| definition source | DrugBank Database
|
| prefixIRI | obo2:dinto_2570
|
| Gene | tgfb1
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |