The Drug-Drug Interactions Ontology - cytochrome p450 2a6 - Classes | NCBO BioPortal

The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_2496
Preferred Name	cytochrome p450 2a6
Synonyms	p450 iia3 p450(i) coumarin 7-hydroxylase cypiia6 ec 1.14.14.1 cyp2a3
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	cytochrome p450 2a6
label	cytochrome p450 2a6
is induced by	http://purl.obolibrary.org/obo/CHEBI_41879 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/dinto_DB01351 http://purl.obolibrary.org/obo/CHEBI_50922 http://purl.obolibrary.org/obo/CHEBI_28077
metabolizes	http://purl.obolibrary.org/obo/CHEBI_65353 http://purl.obolibrary.org/obo/CHEBI_5864 http://purl.obolibrary.org/obo/CHEBI_3219 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_66964 http://purl.obolibrary.org/obo/CHEBI_39867 http://purl.obolibrary.org/obo/CHEBI_3655 http://purl.obolibrary.org/obo/CHEBI_5147 http://purl.obolibrary.org/obo/CHEBI_4027 http://purl.obolibrary.org/obo/CHEBI_10110 http://purl.obolibrary.org/obo/CHEBI_31633 http://purl.obolibrary.org/obo/dinto_DB01085 http://purl.obolibrary.org/obo/CHEBI_31403 http://purl.obolibrary.org/obo/CHEBI_5615 http://purl.obolibrary.org/obo/dinto_DB04841 http://purl.obolibrary.org/obo/CHEBI_18723 http://purl.obolibrary.org/obo/CHEBI_18358 http://purl.obolibrary.org/obo/CHEBI_3766 http://purl.obolibrary.org/obo/CHEBI_7565 http://purl.obolibrary.org/obo/CHEBI_15367 http://purl.obolibrary.org/obo/CHEBI_31225 http://purl.obolibrary.org/obo/CHEBI_3720 http://purl.obolibrary.org/obo/CHEBI_50730 http://purl.obolibrary.org/obo/CHEBI_8050 http://purl.obolibrary.org/obo/CHEBI_44915 http://purl.obolibrary.org/obo/CHEBI_6413 http://purl.obolibrary.org/obo/CHEBI_408174 http://purl.obolibrary.org/obo/dinto_DB01037 http://purl.obolibrary.org/obo/CHEBI_9130 http://purl.obolibrary.org/obo/CHEBI_17026 http://purl.obolibrary.org/obo/dinto_DB00690 http://purl.obolibrary.org/obo/dinto_DB01028 http://purl.obolibrary.org/obo/CHEBI_6456 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/CHEBI_46345 http://purl.obolibrary.org/obo/CHEBI_63613 http://purl.obolibrary.org/obo/dinto_DB01544 http://purl.obolibrary.org/obo/CHEBI_46195 See more See less
Definition	Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase
type	http://www.w3.org/2002/07/owl#Class
is inhibited by	http://purl.obolibrary.org/obo/CHEBI_3216 http://purl.obolibrary.org/obo/dinto_DB06712 http://purl.obolibrary.org/obo/CHEBI_50673 http://purl.obolibrary.org/obo/CHEBI_5141 http://purl.obolibrary.org/obo/CHEBI_2950 http://purl.obolibrary.org/obo/CHEBI_2955 http://purl.obolibrary.org/obo/dinto_DB00170 http://purl.obolibrary.org/obo/dinto_DB01085 http://purl.obolibrary.org/obo/CHEBI_3750 http://purl.obolibrary.org/obo/CHEBI_3752 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/CHEBI_18723 http://purl.obolibrary.org/obo/CHEBI_18358 http://purl.obolibrary.org/obo/CHEBI_68584 http://purl.obolibrary.org/obo/CHEBI_3764 http://purl.obolibrary.org/obo/dinto_DB01011 http://purl.obolibrary.org/obo/dinto_DB06729 http://purl.obolibrary.org/obo/dinto_DB01361 http://purl.obolibrary.org/obo/CHEBI_100246 http://purl.obolibrary.org/obo/dinto_DB01110 http://purl.obolibrary.org/obo/CHEBI_6413 http://purl.obolibrary.org/obo/CHEBI_41922 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/CHEBI_50122 http://purl.obolibrary.org/obo/CHEBI_64312 http://purl.obolibrary.org/obo/CHEBI_8378 http://purl.obolibrary.org/obo/CHEBI_439329 http://purl.obolibrary.org/obo/CHEBI_64323 http://purl.obolibrary.org/obo/dinto_DB01026 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/CHEBI_47781 http://purl.obolibrary.org/obo/CHEBI_2679 http://purl.obolibrary.org/obo/dinto_DB00951 http://purl.obolibrary.org/obo/CHEBI_2668 See more See less
Synonym	p450 iia3 p450(i) coumarin 7-hydroxylase cypiia6 ec 1.14.14.1 cyp2a3 See more See less
OrganismClass	human
xref	UniProt ID:P11509 DrugBank:5718
definition source	DrugBank Database
prefixIRI	obo2:dinto_2496
related with	http://purl.obolibrary.org/obo/dinto_DB04665 http://purl.obolibrary.org/obo/dinto_DB07621 http://purl.obolibrary.org/obo/dinto_DB07609 http://purl.obolibrary.org/obo/dinto_DB07623 http://purl.obolibrary.org/obo/dinto_DB07617
Gene	cyp2a6
subClassOf	http://purl.obolibrary.org/obo/dinto_000130 http://purl.obolibrary.org/obo/dinto_000128

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